1538 Efficacy of topical mugworts in cosmetics and treatment of dermatologic diseases: A systematic review

The genus Artemisia contains dozens of species known as “Mugworts” which have recently been marketed novel ingredients in the treatment dermatologic diseases and enhancement skin health. Over 100 products include Mugwort derivatives claiming to “repair heal skin” “make clean clear.” Due conflicting evidence eruption usage, we performed a systematic review available literature concerning topical their safety efficacy cosmetic appearance various diseases. Using Boolean operators on PubMed, 1116 publications were originally identified, 32 papers met final inclusion criteria. All reviewed demonstrated significant benefits from application including prevention carcinogenesis via inhibition ROS tumor promoters, well reduced inflammation, contact atopic dermatitis, antimicrobial potential, photoprotective effects. A. vulgaris, most commonly used Mugwort, was particularly effective at increasing turnover collagen synthesis, inhibiting metalloproteinases, improving textural antiwrinkle results. Sensitization reactions absent after 3 weeks for all nearly dosages. Future research must be expanded more human models longitudinal improvements/side effects properly direct dermatological recommendations patients skincare product users.